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R.m. (raymond) Schiffelers


Pharmaceutical sciences - Pharmaceutics
Utrecht University
Netherlands

Biography

I obtained my PhD degree from Erasmus University Medical Center Rotterdam, The Netherlands. My thesis focused on liposomal targeting of antimicrobial agents. From 2000-2011, I worked at the dept Pharmaceutics of Utrecht University working on polymers, micelles and liposomes, loaded with small molecular weight drugs as well as biologicals, targeting a variety of diseases. Within this period, I spent 2002-2003 working for Intradigm Co. (USA) on formulations for in vivo targeting of siRNA. In 2007, I obtained a Vidi grant from NWO to start my own research line, in 2009 I received the Galenus Research Award for my drug delivery work and in 2010 was awarded an ERC Starting Grant (consolidator phase) to investigate extracellular vesicles for drug delivery. In 2011, I moved to University Medical Center Utrecht where I complement my research lines on drug targeting with investigations on nanoparticles in diagnostic applications.

Research Interest

Cardiovascular Research

Publications

  • Allijn, Iris E., Vaessen, Stefan F C, Quarles Van Ufford, Linda C., Beukelman, Kees J., De Winther, Menno P J, Storm, G & Schiffelers, Raymond M. (01.05.2016). Head-to-Head comparison of anti-inflammatory performance of known natural products in vitro. PLoS One, 11 (5).

  • Allijn, Iris E., Schiffelers, Raymond M. & Storm, G (15.06.2016). Comparison of pharmaceutical nanoformulations for curcumin - Enhancement of aqueous solubility and carrier retention. International Journal of Pharmaceutics, 506 (1-2), (pp. 407-413) (7 p.).

  • Allijn, Iris E., Czarny, Bertrand M S, Wang, Xiaoyuan, Chong, Suet Yen, Weiler, Marek, da Silva, Acarilia Eduardo, Metselaar, Josbert M., Lam, Carolyn Su Ping, Pastorin, Giorgia, de Kleijn, Dominique P V, Storm, G, Wang, Jiong Wei & Schiffelers, Raymond M. (10.02.2017). Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction. Journal of Controlled Release, 247, (pp. 127-133) (7 p.).

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