Johannes Hohlbein
Professor
Department of Agrotechnology and Food Sciences
Wageningen University
Netherlands
Biography
After obtaining a Ph.D. in Physics (2008, Universitaet Halle-Wittenberg), I worked as a postdoc in the ‘Gene Machines’ group of Achilles Kapanidis at the University of Oxford. As of October 2012, I am an assistant professor in the Laboratory of Biophysics at Wageningen UR. My lab looks into amazing world of DNA-protein interactions utilizing methods of single-molecule fluorescence spectroscopy.
Research Interest
Biophysics Biotechnology Physics
Publications
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Identifying molecular dynamics in single-molecule FRET experiments with burst variance analysis JP Torella, SJ Holden, Y Santoso, J Hohlbein, AN Kapanidis Biophysical journal 100 (6), 1568-1577
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Alternating-laser excitation: single-molecule FRET and beyond J Hohlbein, TD Craggs, T Cordes Chemical Society Reviews 43 (4), 1156-1171
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Surfing on a new wave of single-molecule fluorescence methods J Hohlbein, K Gryte, M Heilemann, AN Kapanidis Physical biology 7 (3), 031001
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Defining the limits of single-molecule FRET resolution in TIRF microscopy SJ Holden, S Uphoff, J Hohlbein, D Yadin, L Le Reste, OJ Britton, ... Biophysical journal 99 (9), 3102-3111
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Conformational transitions in DNA polymerase I revealed by single-molecule FRET Y Santoso, CM Joyce, O Potapova, L Le Reste, J Hohlbein, JP Torella, ... Proceedings of the National Academy of Sciences 107 (2), 715-720
