Dr Olivier Lamiable
Senior Research Fellow
Department of General Science
Malaghan Institute of Medical Research
New Zealand
Biography
At the University of Orleans, France, Dr Olivier Lamiable achieved his License degree, Master’s degree and PhD. Completed early 2010, his PhD focused on epigenetic regulation of the embryonic development of Drosophila melanogaster (the common fruit fly). His research identified and characterized protein partners of the ortholog of HMGB1 that are involved in this process. Following this, Dr Lamiable studied the antiviral responses of D. melanogaster at Institute de Biologie Moleculaire et Cellulaire in Strasbourg, France. Dr Lamiable was drawn to the Malaghan Institute by the opportunity to transfer his skills into research more applicable to human health. In March 2016, he became a Postdoctoral Research Fellow in our Immune Cell Biology Programme, led by Professor Franca Ronchese, with a specific focus on allergies.
Research Interest
Allergies involve the immune system overreacting to harmless substances. Over a third of New Zealanders experience allergies in their lifetime, at differing levels of severity. These can range from minor inconveniences to life threatening conditions. While there are various drugs to manage symptoms, curative treatments for allergies do not yet exist. I am interested in understanding the processes that begin an allergic reaction. I particularly focus on the genetic regulation of the immune system and how dendritic cells function in allergic reactions.
Publications
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Connor LM, Tang SC, Cognard E, Ochiai S, Hilligan K, Old S, Pellefigues C, White R, Patel D, Smith A, Eccles D, Lamiable O, McConnell M, Ronchese F (2017) Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles. J Exp Med.
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Connor LM, Lamiable O, Ronchese F (2017) Fetal dendritic cells give mum a break. Immunol Cell Biol.
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White R, Pellefigues C, Ronchese F, Lamiable O, Eccles D (2017) Investigation of chimeric reads using the MinION. F1000Research.
