Dr James Ussher
Immunologist
Microbiology & Immunology
Otago University
New Zealand
Biography
Otago 1999 PhD, Auckland 2010 FRCPA, 2010 Oxford Nuffield Medical Fellow, Oxford University, UK . clinical specialty is medical microbiology.
Research Interest
Applied and molecular immunology, medical microbiology, vaccines. My research interest is infection and immunity. In particular, I am interested in mucosal associated invariant T (MAIT) cells, their role in antibacterial immunity, and how they might be harnessed to prevent or treat bacterial infection. I have been involved in several fundamental discoveries in MAIT cell biology. I am also interested in the antimicrobial resistance, in particular its rapid detection, characterisation, and transmission, especially in Enterobacteriaceae.
Publications
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Ussher JE, Phalora P, Cosgrove C, Hannaway R, Rauch A, Gunthard HF, Goulder P, Phillips RE, Willberg CB and Klenerman P. Molecular analyses define Vα7.2-Jα33+ MAIT-cell depletion in HIV infection: a case-control study. Medicine, 2015; 94(29):e1134. IF 5.723
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Gough N, and Ussher JE. An outbreak of mumps-like illness. New Zealand Public Health Surveillance Report, 2015; 13(4):2.
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Ussher JE, van WilgenburgB, Hannaway RF, Ruustal K, Phalora P, Kurioka A, Hansen TH, Willberg CB, Phillips RE, Klenerman P. TLR signalling in human antigen-presenting cells regulates MR1-dependent activation of MAIT cells. European Journal of Immunology, accepted. IF 4.97
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Saeidi A, Ellegård R, Kong Y, Hong T, Velu V, Ussher JE, Larsson M, and Shankar EM. Functional role of MAIT cells in HIV infection. Journal of Leukocyte Biology, accepted. IF 4.29
