Keith Ireton
Professor
Microbiology & Immunology
Otago University
New Zealand
Biography
My laboratory studies molecular mechanisms of virulence of the food-borne pathogen Listeria monocytogenes. One ongoing project focuses on understanding the process by which Listeria induces its internalization into host human cells. Another project examines how Listeria spreads from infected human cells to surrounding healthy cells.
Research Interest
Medical microbiology and microbial pathogenesis, cellular microbiology
Publications
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Dowd, G.C., Bhalla, M., Kean, B., Thomas, R., and Ireton, K. 2016. Role of host type IA phosphoinositide 3-kinase pathway components in invasin-mediated internalization of Yersinia enterocolitica. 2016. Infect. Immun. 84: 1826-1841.
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Bhalla, M., Law, D., Dowd, G.C., and Ireton, K. 2017. Host serine/threonine kinases mTOR and PKC-alpha promote inlB-mediated entry of Listeria monocytogenes. Infect. Immun. Jun 20;85(7).
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Van Ngo, H., Bhalla, M., Chen, D.Y., and Ireton, K. 2017. A role for host exocytosis in InlB-mediated internalization of Listeria monocytogenes. Cell. Microbiol.
