Alexander Mclellan
Professor
Microbiology & Immunology
University of Otago
New Zealand
Biography
CAR T cells (Chimeric Antigen Receptor-modified T cells) against solid tumours. Cancer stem cell antigens, tumour-associated antigens, and tumour microenvironment metabolites. Cytokine and chemokine receptor strategies to improve T cell function against solid tumours.
Research Interest
Cancer immunobiology
Publications
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Muhsin-Sharafaldine R-M, Kennedy BR, Saunderson SC, Buchanan CR, Dunn AC, Faed JM, McLellan AD. Mechanistic insight into the procoagulant activity of tumor-derived apoptotic vesicles. Biochimica Biophysica Acta – General Subjects. 2017 Feb;1861(2):286-295
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Muhsin-Sharafaldine MR, Saunderson SC, Dunn AC, McLellan AD. Melanoma growth and lymph node metastasis is independent of host CD169 expression. Biochem Biophys Res Commun. 2017 Mar 27. pii: S0006-291X(17)30613-7.
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Saunderson SC, McLellan AD. Role of lymphocyte subsets in the immune response to primary B cell-derived exosomes. Journal of Immunology 2017. MS ID: 16-01537FLR. In press.
