Mike Stratton
Director of the Wellcome Trust Sanger Institute an
Cancer Genome Project at the Wellcome Trust Sanger Institute
Trust Sanger Institute
Norway
Biography
Mike Stratton is the Director of the Wellcome Trust Sanger Institute and Chief Executive Officer of the Wellcome Genome Campus. His primary research interests have been in the genetics of cancer. His early research focused on inherited susceptibility. Mike mapped and identified the major high-risk breast cancer susceptibility gene BRCA2 and subsequently a series of moderate-risk breast cancer and other cancer susceptibility genes.
Research Interest
In 2000 Mike initiated the Cancer Genome Project at the Wellcome Trust Sanger Institute which conducts systematic genome-wide searches for somatic mutations in human cancer. Through these studies he discovered somatic mutations of the BRAF gene in malignant melanoma and several other mutated cancer genes in lung, renal, breast and other cancers. He has described the basic patterns of somatic mutation in cancer genomes revealing underlying DNA mutational and repair processes.
