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Syed Sikander Azam

 Assistant Professor
National Centre for Bioinformatics
Quaid-i-Azam University
Pakistan

Biography

Dr. Sikander has 46 publications in internationally well known journals and two publications of national journals on his credit. He has accomplished his Ph.D from the University of Innsbruck, Austria, in the field of Theoretical and Computational Chemistry. Current research interests lied in the field of Computational Biochemistry.In particular, Molecular Docking and Molecular Dynamic (MD) Simulations of proteins for understanding structural and dynamical aspects of the biological system. The application of Molecular Mechanic ( MM) , and Hybrid Quantum Mechanical / Molecular Mechanical (QM/MM) Molecular Dynamic (MD), and Quantum Mechanical Charge Field (QMCF) Molecular Dynamic Simulations for the evaluation of structural and dynamical properties of biologically and industrially important ions in aqueous solution are another dimensions of his interests. He is currently establishing a computational facility lab at the National Centre for Bioinformatics which helps to maintain the synergistic relationship with the experimental research work carried out on various proteins at the resource lab of the institute. 

Research Interest

Computational Biochemistry

Publications

  • S., Ali,B., Amina,S., Anwar,R., Minhas,N., Parveen,U., Nawaz, S.S, Azam & Abbasi A.A., (2016), Genomic features of human limb specific enhancers. Genomics. on of novel transcriptional enhancers involved in regulating human GLI3 expression during early development. Development, growth & differentiation, 57(8), 570-580. 

  • Zawawi N.K.N.A, Muhammad Taha, Ahmat N, Wadood A, Ismail N.H, Rahim F, Azam, S. S., Abdullah N, (2016). Benzimidazole derivatives as new α-glucosidase inhibitors and in silico studies. Bioorganic Chemistry. 64, 29–36. 

  • Abro, A., & Azam, S. S.(2016). Binding free energy based analysis of arsenic (+ 3 oxidation state) methyltransferase with S-adenosylmethionine. Journal of Molecular Liquids, 220, 375-382.

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