Jacek Jaworski

Biography

 1996 MSc in Biology, Department of Genetics, Warsaw University, Poland, 2001 PhD in Molecular Neurobiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland, 2010 DSc Habil in Molecular Biology, Warsaw University, Poland, 2014 Professor of Biological Sciences, nomination by the President of the Republic of Poland

Research Interest

 The research of our team concentrates on the role of protein kinase mammalian Target of Rapamycin (mTOR) in the control of proper neuronal morphology in health and disease. Establishing proper neuronal morphology is required for proper brain function. Therefore, the mechanisms of axon targeting, dendritic arbor patterning, proper cell contact formation, and maintenance of plasticity of neuronal connectivity are at the center of interest of molecular neurobiology. Dendrites are the main site of information input onto neurons, and dendritic arbor shape is one of the crucial factors that determine how signals that originate from individual synapses are integrated. In fact, several neurodevelopmental pathologies are characterized by abnormalities in dendritic tree structure.