Matthias Bochtler
Professor, Group Leader
Laboratory of Structural Biology
International Institute of Molecular and Cell Biology in Warsaw
Poland
Biography
1995 MSc in Experimental Physics, Munich University, Germany, 1999 PhD in Biochemistry, Technical University of Munich, Germany, 2006 DSc Habil, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań, Poland,2009 Professor of Biological Sciences, nomination by the President of the Republic of Poland
Research Interest
Our group currently works on sequence- and modificationspecific protein-nucleic acid interactions. With an FNP Team grant to support our work, the focus is now almost exclusively on DNA methylation and hydroxymethylation. These modifications are present in prokaryotes and eukaryotes, but they have very different roles in these organisms. Our group seeks to exploit the prokaryotic biology of DNA methylation and hydroxymethylation to develop tools for the study of these modifications in eukaryotes, particularly zebrafish and mice. In 2012, our efforts were concentrated on one story that emphasizes the deep evolutionary roots of DNA methylation.