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Dr. Patrycja Dynarowicz-Łątka

Professor
Chemistry
Jagiellonian University
Poland

Biography

Dr. Patrycja Dynarowicz-Łątka is the Professor of Chemistry in Jagiellonian University. Her research is focused on the properties of gasliquid and gas-solid interfaces, with interest on: 1. Highly ordered organic thin fi lms. Using Langmuir-Blodgett deposition and self-assembly, fi lms can be formed as thin as a single molecular layer with very good control over structure. Highly ordered, defect-free fi lms with controllable molecular orientation and architecture can thus be fabricated and applied in optical and molecular electronic devices and in highly specifi c chemical sensors. 2. Molecular interactions in monolayers. In this area of research cellular membranes are modelled with Langmuir monolayers and the interactions between membrane components and various biomolecules are investigated. The work involves polyene antibiotics (amphotericin B, nystatin) and new generation anticancer drugs (miltefosine, edelfosine), and is done to gain understanding of their mode of action at membrane level. 3. Synthesis and physico-chemical characterization of surface active molecules. In this project novel surfactants of classical amphiphilic structure as well as non-typical surface active compounds (e.g. di- or tri-block semifl uorinated alkanes) are synthesized. For their characterization various optical and spectroscopic methods are used.

Research Interest

General Chemistry

Publications

  • HÄ…c-Wydro K., Dynarowicz-Łątka P., Interaction between nystatin and natural membrane lipids in Langmuir monolayers – the role of phospholipids in the mechanism of polyene action, Biophys. Chem., 123, 154–161, 2006.

  • Broniatowski M., Dynarowicz-Łątka P., Interactions of a fl uoroaryl surfactant with hydrogenated, partially fl uorinated and perfl uorinated surfactants at the air/water interface, Langmuir, 22, 6622–6628, 2006.

  • Broniatowski M., Dynarowicz-Łątka P., Semifl uorinated alkanes – primitive surfactants of fascinating properties, Adv. Colloid Interfac. Sci., 138, 63–83, 2008.

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