Ana Margarida Lima Lopes
Researcher
Immunogenetics, Microbes and Infectious Diseases
CIBIO, Centro de Investigacao em Biodiversidade e Recursos Geneticos
Portugal
Biography
I am interested in studying the co-evolution between the new RHDV variant (RHDV2) and the host by taking advantage of the recent emergence of this variant. The main focus of my work has been evaluating the adaptation of RHDV2 to rabbit populations with distinct genetic background, characterizing the virulence of RHDV2 strains and compare the host immune response to RHDV2-induced disease with infection by other pathogenic or non-pathogenic rabbit caliciviruses.
Research Interest
Evaluating the adaptation of RHDV2 to rabbit populations with distinct genetic background, characterizing the virulence of RHDV2 strains and compare the host immune response to RHDV2-induced disease with infection by other pathogenic or non-pathogenic rabbit caliciviruses
Publications
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Almeida T, Lopes AM, Magalhães MJ, Neves F, Pinheiro A, Gonçalves D, Leitão M, Esteves PJ, Abrantes J (2015) Tracking the evolution of the G1/RHDVb recombinant strains introduced from the Iberian Peninsula to the Azores islands, Portugal. Infection Genetics and Evolution, 34: 307-313.
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Monterroso P, Garrote G, Serronha A, Santos E, Delibes-Mateos M, Abrantes J, Pérez-de-Ayala R, Silvestre F, Carvalho J, Vasco I, Lopes AM, Maio E, Magalhães MJ, Mills LS, Esteves PJ, Simón MA, Alves PC (2016) Disease-mediated bottom-up regulation: An emergent virus affects a keystone prey, and alters the dynamics of trophic webs. Sientific Reports, 6: 36072.
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Lopes AM, Silverio D, Magalhaes MJ, Areal H, Alves PC, Esteves PJ, Abrantes J (2017) Characterization of old RHDV strains by complete genome sequencing identifies a novel genetic group. Scientific Reports, 7: 13599.
