Luka Alexander Clarke
Chemistry
University of Lisbon
Portugal
Biography
Luka Clarke studied Zoology at Bristol University, and then obtained his PhD from London University (Molecular Endocrinology). His post-doctoral work at CGH / INSA in Lisbon concerned alternative splicing of human mismatch repair genes. He later joined the Cystic Fibrosis (CF) group at the University of Lisbon, where he worked on two collaborative EU projects on the development of lab-on-a-chip systems for CF diagnosis. He was awarded a Science 2008 research position at FCUL (2009-2014). He is now an invited adjunct professor at FCUL and is currently engaged at BioISI in the study of mutation specific expression of the CFTR gene and its implications in personalized CF therapy.
Research Interest
Cystic Fibrosis related gene expression; Allele-specific CFTR mRNA abundance; Personalized medicine; Omics and disease markers; Bioinformatic applications for high throughput data.