Margarida D Amaral
University of Lisbon
Margarida Amaral is Full Professor of Molecular Biology at the Faculty of Sciences, University of Lisbon and Coordinator of BioISI research center. EMBO member (2014). Habilitation (2006). PhD in Molecular Genetics (1993). BSc in Chemistry / Biochemistry (1983).
MD Amaral's lab has a major focus on molecular and cellular mechanisms of biogenesis, traffic and degradation of wt and mutant CFTR protein, which when mutated causes the genetic disease Cystic Fibrosis (CF). To understand CF mechanisms globally we use transcriptomics, proteomics and functional genomics (functional siRNA screens). Our results translate into the clinic for better CF diagnosis, prognosis and personalized therapies.