Margarida Gama Carvalho

Biography

Academic education 1994 Degree in Biology, FCULisboa 2000 Evidence of Pedagogical Aptitude and Scientific Capability (Molecular and Cell Biology), FMULisboa 2003 PhD in Biomedical Sciences (Molecular and Cellular Biology), FMULisboa; 2004 Postdoctoral degree in Molecular Biology, Dana Farber Cancer Institute / Harvard Medical School, MA, USA Current position 2011 Assistant Professor, FC ULisboa 2015 Coordinator of the Gene Expression and Regulation Unit, BioISI, ULisboa 2015 RNA Group Leader Biology and Bioinformatics, BioISI, ULisboa 2015 Coordinator of the Communication and Outreach Working Group, BioISI, ULisboa Previous positions 2016 Visiting assistant Professor (in sabatical leave) Department of Cell Biology, Harvard Medical School, MA, USA 2009-14 Gene Expression and Bioinformatics Unit Coordinator, BioFIG, FCUL 2009-14 Group Leader RNA Biology and Bioinformatics, BioFIG, FCUL 2003-11 Assistant Professor, FMUL 2003-04 Visiting researcher, Dana Farber Cancer Institute / Harvard Medical School, MA, USA 2000-03 Assistant, FMUL 1996-00 Trainee Assistant, FMUL 1995-96 Scholarship for Scientific Research of the Praxis XXI Program, FMUL Awards and awards 1st Prize L'Oreal Portugal / Unesco for Women in Science (2004). Human Frontiers Science Program Fellowship (2003); Short-term scholarship from the Calouste Gulbenkian Foundation (2003).

Research Interest

Study of post-transcriptional regulation networks of RNA-dependent gene expression and RNA binding proteins in vertebrates through molecular biology, transcritomics and bioinformatics approaches, with emphasis on the immune and nervous system; regulatory biogenesis dependent on microRNAs and mechanisms of regulation of splicing, stability and translation of the mRNA; characterization of gene expression profiles by large scale methodologies and bioinformatics analysis; development of therapeutic strategies based on control of gene expression and new generation sequencing applications; mechanisms of diseases associated with RNA metabolism, with emphasis on neurodegenerative diseases. Pathogen-host interactions, focusing on HIV.