Essam M. Abdelalim
Hamad bin Khalifa University
Dr. Essam M. Abdelalim received his Ph.D. in Medical Science from Shiga University of Medical Science, Japan (2009), where he was also appointed as an assistant professor (2008-2009). After his Ph.D., he was awarded a Postdoctoral Fellowship from the Japan Society for Promotion of Science (JSPS) (2009- 2011).
Generation of patient-specific induced pluripotent stem cells (iPSCs) Differentiate human pluripotent stem cells (hPSCs) into cell types relevant to a specific disease to establish an in vitro model of the disease Using hPSCs as a translational in vitro model to study the pathophysiology of diabetes. Studying human pancreatic islet development using hPSCs Understanding the molecular mechanisms underlying cellular reprogramming and pluripotency
Abdelalim EM, Tooyama I (2012). NPR-C protects embryonic stem cells from apoptosis by regulating p53 levels. Stem Cells and Development, 21 (8): 1264-1271. 2012
Abdelalim EM, Tooyama I (2014). Knockdown of p53 suppresses Nanog expression in embryonic stem cells. Biochem. Biophys. Res. Commun. 443 (2): 652-657. 2014
Magdeldin S, Yamamoto T, Tooyama I, Abdelalim EM (2014). New proteomic insights on the role of NPR-A in regulating self-renewal of embryonic stem cells. Stem Cell Reviews and Reports, 2014 Aug; 10 (4): 561-72. 2014