Jean-charles
associate professor
life science
Hamad bin Khalifa University
Qatar
Biography
Dr. Grivel's work has been centered on defining the relationship between viral phenotype and viral pathogenesis in several viral diseases, and in particular in HIV infection. He has developed several explant culture models of human tissues in which I have studied co-infections of HIV with its most common co-pathogens.
Research Interest
The development of experimental model of human infection and the application of flow cytometric nanotechnologies technologies to the discovery of disease biomarkers.
Publications
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Lisco A, Introini A, Munawwar A, Vanpouille C, Grivel JC, Blank P, Singh S, Margolis L. HIV-1 imposes rigidity on blood and semen cytokine networks. Am J Reprod Immunol 2012;68:515-21 2012
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Arakelyan A, Fitzgerald W, Margolis L, Grivel JC. Nanoparticle-based flow virometry for the analysis of individual virions The Journal of clinical investigation 2013;123:3716-27. 2013
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Romero R, Grivel JC, Tarca AL, Chaemsaithong P, Xu Z, Fitzgerald W, Hassan SS, Chaiworapongsa T, Margolis L. Evidence of Perturbations of the Cytokine Network in Preterm Labor. American journal of obstetrics and gynecology 2015. 2015