Hamad bin Khalifa University
Dr. Decock received her PhD in Medical Sciences in 2008 from the Catholic University of Leuven (KULeuven), Belgium. Her PhD work focused on the clinical relevance of proteases, in particular matrix metalloproteinases and cathepsins, in breast cancer.
Dr Decock her research focuses on the molecular mechanisms underlying the aggressive behavior and poor clinical phenotype of triple negative breast cancer. In addition to basic biological research, she also conducts translational research into novel adoptive T cell therapeutic modalities for triple negative breast cancer.
Van Belle V, Decock J, Hendrickx W, Brouckaert O, Pintens S, Moerman P, Wildiers H, Paridaens R, Christiaens MR, Van Huffel S, Neven P. Short term prognostic index for breast cancer: NPI or Lpi. Pathol Res Int 2010; 2011:918408. doi: 10.4061/2011/918408.
Thirkettle S, Decock J, Arnold H, Pennington CJ, Jaworski DM, Edwards DR. Matrix metalloproteinase-8 (collagenase-2) induces the expression of interleukins-6 and -8 in breast cancer cells. J Biol Chem. 2013, 288(23):16282-94.
Kelwick R, Wagstaff L, Decock J, Roghi C, Cooley LS, Robinson SD, Arnold H, Gavrilović J, Jaworski DM, Yamamoto K, Nagase H, Seubert B, Krüger A, Edwards DR. Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by A disintegrin and metalloproteinase with thrombospondin motifs-15 (ADAMTS-15). Int J Cancer 2014, doi: 10.1002/ijc.29129.