Xavier Leroy
Director
Drug Discovery
iTeos Therapeutics
Romania
Biography
Xavier Leroy was a pioneer in several approaches like the application of Phage-Display to membrane proteins, allowing the discovery of highly potent modulators, agonists and antagonists. As a target hunter, he paired 4 important peptides/neuropeptides on GPCRs. In recent years, Xavier Leroy was a key actor of the emerging research field of Resolution of Inflammation. He demonstrated the importance of this pathway through the discovery and validation of different targets and molecules. He was developing assays allowing a better characterization of the molecules and the understanding of the associated pharmacology (e.g., residence time, insurmountably, biased agonists, in-vivo target engagement).
Research Interest
Biochemistry
