Ekaterina Khrameeva
Research Scientist
Material Science
Skoltech
Russian Federation
Biography
Ekaterina graduated from the Department of Bioengineering and Bioinformatics, Moscow State University, in 2009. She completed her postgraduate project at the Institute for Information Transmission Problems, Russian Academy of Sciences, and defended her thesis titled “Distant interactions in eukaryotic genomes and regulation of alternative splicing” in 2015. During her postgraduate studies, Ekaterina worked as a bioinformatician at the Justus Liebig University (Giessen), the Helmholtz Zentrum München (Munich), the Partner Institute for Computational Biology (Shanghai), and the Leiden University Medical Center (Netherlands). Ekaterina won several competitions and research grants, and published seventeen papers.
Research Interest
Identification of biological features associated with human development and lifespan using high-throughput data analysis. In this project, we measure gene expression, metabolite levels and genotypes in samples of human brain, as well as in other tissues and species (for comparison) using various high-throughput methods, such as DNA sequencing, RNA-seq, and mass-spectrometry. We analyze these data to study: – molecular markers of cognitive disorders; – human brain metabolome; – evolution of brain metabolome, compared to other tissues; – functions of human-specific proteins via analysis of humanized mice metabolome.
