Moni Nader
Assistant Professor
Physiology
Alfaisal University
Saudi Arabia
Biography
Dr Moni Nader is an Assistant Professor of Physiology at Alfaisal Medical School. He also serves as an Adjunct Scientist at the Department of Genetics at KFSHRC. Dr Nader earned his PhD in Cell Biology from the University of Sherbrooke (Canada) and accomplished a Postdoctoral Training in Molecular Cardiology at the University of Ottawa Heart Institute (Canada) where he was supported by the Heart and Stroke Foundation of Canada. Dr Nader's laboratory is primarily focused on the role of membrane/scaffold proteins in regulating the excitation-contraction coupling in cardiomyocytes. His research team is dealing with fundamental aspects of calcium homeostasis and its role in cardiac disease namely arrhythmias. His recent work established a role for the membrane protein SLMAP in myocardial contraction and calcium homeostasis. He is also exploring the dynamics of the scaffold protein Striatin in regulating calcium signaling and cardiomyocytes contraction.
Research Interest
Genetics, Physiology
Publications
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Bkaily G, Avedanian L, Al - Khoury J, Provost C, Nader M , D'Orleans - Juste P and Jacques D . Nuclear membrane receptors for ET - 1 in cardiovascular function. American Journal of Physiology - Regulatory, Integrative and Comparative Physi ology 300: R251 - R263, 2011.
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Nader M , Westendorp B, Hawari O, Salih M, Stewart AFR, Leenen FHH and Tuana BS . Tail - anchored membrane protein SLMAP is a novel regulator of cardiac function at the sarcoplasmic reticulum. American Journal of Physiology - Heart and Circulatory Physiology 302: H1138 - H1145, 2012.
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Westendorp B, Major JL, Nader M , Salih M, Leenen FHH and Tuana BS . The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. The FASEB Journal (6):2569 - 79 , 2012 .
