Sudhakar Jha
Principal Investigator
cancer scientists
Cancer Science Institute of Singapore
Singapore
Biography
SUDHAKAR JHA, is currently working as Principal Investigator, Cancer Science Institute of Singapore. Dr Jha is interested in studying the regulation of chromatin remodeling complexes and their role in cancer prevention. His research focuses on understanding the function of TIP60 (a histone acetyltransferase) as a tumor suppressor. Dr Jha has discovered TIP60 to be down-regulated by E6, a viral oncogene expressed by human papillomavirus (HPV). Interestingly, TIP60 is down-regulated in multiple cancers. Using TIP60 as a candidate molecule, he plans to investigate how deregulation of this chromatin remodeling complex can lead to cancer.
Research Interest
Studying the regulation of chromatin remodeling complexes and their role in cancer prevention
