Hausenloy, Derek
Professor
Cardiovascular & Metabolic Disorders
Duke-NUS Graduate Medical School
Singapore
Biography
He did his PhD in 2004 in University College London.Currently he is working as a Professor in Department of Cardiovascular & Metabolic Disorders.
Research Interest
Cardioprotection,Mitochondria as targets for cardioprotection • Ischaemic preconditioning and postconditioning – underlying signalling pathways, mechanisms and clinical application • Remote ischaemic conditioning – underlying mechanisms and clinical application • Effect of co-morbidities such as diabetes on cardioprotection • Pre-clinical and clinical cardiac MRI and hybrid PET/MR studies to investigate the pathophysiology of acute IRI and assess cardioprotection in the setting of AMI and post-ischaemic heart failure. • Clinical cardioprotection proof-of-concept and multi-centre outcome studies in CABG and AMI patients
Publications
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Yellon DM, Hausenloy DJ. Clinical implications of ischemic pre- and post-conditioning. Nature Clinical Practice Cardiovascular Medicine 2005 Nov;2(11):568-75.
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Hausenloy DJ, Wynne A, Duchen MR, Yellon DM. Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection. Circulation 2004 Apr 13;109(14):1714-7.
