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James, Michael Lucas

James, Michael Lucas
Neurology
Duke-NUS Graduate Medical School
Singapore

Biography

Following residencies in neurology and anesthesiology with fellowships in neurocritical care, neuroanesthesia, and vascular neurology, He joined the faculty in the Department of Anesthesiology at Duke University. Initially through the benefit of a National Institutes of Health training grant award and subsequent mentored funding from the American Heart Association in the Multidisciplinary Neuroprotection Laboratories. In addition,He used the model to evaluate the potential of several novel therapeutics for translation into human clinical trials.

Research Interest

Pursuit of translatable mechanisms of modifying neuro-inflammation after intracerebral hemorrhage to improve long-term functional recovery.

Publications

  • Umeano O, Wang H, Dawson H, Lei B, Umeano A, Kernagis D, James ML. Female gonadal hormone effects on microglial activation and functional outcomes in a mouse model of moderate traumatic brain injury. World J Crit Care Med. 2017;6(2):107-115. PMID: 28529912

  • James ML, Langefeld CD, Sekar P, Moomaw CJ, Elkind MSV, Worrall BB, Sheth KN, Martini SR, Osborne J, Woo D; ERICH Investigators. Assessment of the interaction of age and sex on 90-day outcome after intracerebral hemorrhage. Neurology. 2017 Jul 14. [Epub ahead of print] PMID: 28710330

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