Zwi Berneman
Medicine
ExoCyte Therapeutics Pte
Singapore
Biography
Prof. Berneman, is Professor of Hematology and Head of the Laboratory of Experimental Hematology at the University of Antwerp and Head of the Division of Hematology at the Antwerp University Hospital. The main focus of his research is vaccination with immunogenic dendritic cells for malignant disease (acute myeloid leukemia, glioblastoma, mesothelioma, metastatic breast cancer) and infections (HIV, cytomegalovirus) and with tolerogenic dendritic cells in multiple sclerosis. His laboratory has pioneered mRNA electroporation as a clinically safe gene transfer methodology and has applied it to the fields of dendritic cells, T-lymphocytes and stem cells. He has been conducting clinical trials with cultured cells as advanced therapy medicinal products (ATMP) since 2005. For this, he helped establish the Center for Cell Therapy and Regenerative Medicine (CCRG) of which he is the Medical Director, at the Antwerp University Hospital and for which he obtained a Good Manufacturing Practices (GMP) Certification and Production License for dendritic cells and limbal epithelial cells from the (Belgian) Federal Agency for Medicines and Health Products.
Research Interest
Medicine and Pharmaceutical