Daniel M Messerschmidt

Biography

 Daniel M. Messerschmidt obtained his master in biochemistry at the Max Planck Institute for Developmental Biology and the University of Tuebingen (Germany) where he studied organ formation and protein interactions in nematodes. He then embarked on his doctoral work at the Max Planck Institute for Immunobiology (Freiburg, Germany) studying differentiation events in mouse preimplantation embryos. His work on lineage segregation and differentiation in the blastocyst and embryonic stem cells ultimately showed a non-cell autonomous requirement of the pluripotency transcription factor NANOG for primitive endoderm formation in vivo.  In 2009 he joined the laboratory of Barbara Knowles and Davor Solter at the A*STAR Institute of Medical Biology (Singapore) to follow his interests in epigenetic aspects of differentiation and early embryonic development. He addresses epigenetic reprogramming during oocyte-to-embryo transition, an essential measure to ensure totipotency in the mammalian zygote and early embryo.  In 2013, he was awarded an IMCB Junior Investigator (IJI) position to conduct independent research at the Institute of Molecular and Cell Biology where he continued to pursue is investigation on the early epigenetic reprogramming events in mouse embryos. In 2014 he was awarded the prestigious Fellowship by the National Research Foundation (NRF) and is Principal Investigator at IMCB since. He is further Adjunct Assistant Professor at the Department of Biochemistry, Yong Loo Lin School of Medicine, National University, Singapore since 2015.

Research Interest

 Molecular and Cell Biology