Prof Cheah Peh Yean

Biography

Dr Cheah is Co-Director and Senior Scientist of the Colorectal Cancer Research Laboratory at the Department of Colorectal Surgery, Singapore General Hospital. She is an Adjunct A/Prof in Saw Swee Hock School of Public Health as well as Duke-NUS Medical School, National University of Singapore. Dr. Cheah has been actively involved in colorectal cancer research, related to genomics and pathology for over 20 years. She is instrumental in positioning the laboratory at the forefront of colorectal cancer research in the region, focusing on the diverse ethnicity and genetic variation of the Asian populations, thus contributing towards better patient care and public health for Singapore and the region. Recent work has entailed the discovery of new tumor suppressors for APC mutation-negative familial CRC patients via high-density genotyping arrays; potential biomarkers to predict metastasis in early stage CRC via genome-wide expression, mutation and miRNA profiling as well as genome-wide association study to identify risk loci associated with differential response to environmental insults for sporadic CRC. She held numerous competitive national grants as principal investigator since 1997. She is an academic editor for international peer-reviewed journal.

Research Interest

Surgery