Biomedical Sciences
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Biomedical Sciences Experts

Janko Kos

Head of the Department
Department of Biotechnology
Jozef Stefan Institute
Slovenia

Biography

"Dr. Janko Kos, from 2006 Institute Jožef Stefan, Head of the Department of Biotechnology, complementary work till 2005 Faculty of Pharmacy, UL, full professor, vice dean for research work, 1996 - 2005 Krka, dd, Novo mesto, Head of the Department of Planning and Biochemical Research, 1992 - 1996 Jožef Stefan Institute, Postdoctoral Associate, Department of Biochemistry and Molecular Biology. 1984- 1992 Jožef Stefan Institute, Assistant, Department of Biochemistry and Molecular Biology "

Research Interest

Proteolysis, Tumor biology, Immunochemistry, Delivery systems

Publications

  • Machleidt W, Thiele U, Laber B, Assfalg-Machleidt I, Esterl A, Wiegand G, Kos J, Turk V, Bode W. Mechanism of inhibition of papain by chicken egg white cystatin: Inhibition constants of N-terminally truncated forms and cyanogen bromide fragments of the inhibitor. FEBS letters. 1989 Jan 30;243(2):234-8.

  • Kos J, Lah TT. Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer. Oncology reports. 1998 Nov 1;5(6):1349-410.

  • Kocbek P, Obermajer N, Cegnar M, Kos J, Kristl J. Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody. Journal of controlled release. 2007 Jul 13;120(1):18-26.

  • Bode W, Engh R, Musil D, Thiele U, Huber R, Karshikov A, Brzin J, Kos J, Turk V. The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases. The EMBO journal. 1988 Aug;7(8):2593.

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