Biochemistry and Molecular Biology
Jozef Stefan Institute
Dr. Jelena Rajkovič completed phD in2009 from Jozef Stefan Institute. She is working as professor in Jozef Stefan Institute
Our current work involves biochemical characterization of the cysteine proteinases TcAtg4.1 and TcAtg4.2 from the parasite Trypanosoma cruzi, a causing agent of Chagas dieases in humans in Latin America. Our goal is to develop specific substrates for both protein isoforms, which will serve as a platform for the inhibitor synthesis with the aim of preventing human infection and/or pathogenesis of Chagas’ disease. We are also interested in determination of protein-protein interactions in complex protein samples by use of proteomics, with aim to determine binding partners of different atg proteins and to find novel endogenous substrates for autophagins
am Rosengarten T. XXX th Winter School on Proteinases and Their Inhibitors.