Bahareh Honarparvar
Lecturer
Pharmaceutical Sciences
University of Kwazulu-Natal
South Africa
Biography
Dr. Bahareh Honarparvar received her Ph.D. degree in Physical Chemistry (Computational Chemistry) from Iran in 2010. Her Ph.D thesis was about the application of ab initio electronic structure calculations for drug-like compounds. From 2002 up to 2006, she was manager of industrial projects in Ministry of oil as well as Polymer and petrochemical research Centre in Tehran-Iran. In 2007, she was employed as a project manager and educational research member in Institution for Curriculum Development & Educational Innovations, Tehran, Iran till April 2010. After getting her PhD, she started her research on computational HIV drug design as a computational postdoctoral fellow at KwaZulu-Natal University in Durban, South Africa from July 2010 up to June 2013. She is currently appointed as a lecturer in the school of Health Sciences (Pharmaceutical Sciences). Her research interest is mainly on applying computational medicinal chemistry approaches (Molecular Dynamic simulation, molecular docking, binding free energy calculation) to investigate enzyme-inhibitor interactions for synthesizing novel drugs related to different diseases.
Research Interest
Computational Chemistry
Publications
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Makatini MM, Petzold K, Arvidsson PI, Honarparvar B, Govender T, Maguire GE, Parboosing R, Sayed Y, Soliman ME, Kruger HG (2012) Synthesis, screening and computational investigation of pentacycloundecane-peptoids as potent CSA-HIV PR inhibitors.Eur J Med Chem 57:459-467.
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Honarparvar B, Govender T, Maguire GE, Soliman ME, Kruger HG (2014) Integrated approach to structure-based enzymatic drug design: molecular modeling, spectroscopy, and experimental bioactivity. Chem Rev 114(1):493-537.
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Farahani MD, Honarparvar B, Albericio F, Maguire GE, Govender T, Arvidsson PI, Kruger HG (2014) Proline N-oxides: modulators of the 3D conformation of linear peptides through "NO-turns". Org Biomol Chem 12(25):4479-4490.
