Santiago Roura
Researcher Associate
Biomedical Engineering
Centro de Medicina Regenerativa de Barcelona
Spain
Biography
Santiago Roura holds graduate and PhD degree in Biochemistry from the Universitat Autònoma de Barcelona and Universitat de Barcelona, respectively. Since 2002 he is investigating the potential of cell therapies and tissue engineering to recover post-infarcted myocardium in Dr. Bayes-Genis group at Hospital de la Santa Creu i Sant Pau (Barcelona) and Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol (Badalona). Moreover, he is one among the researchers envisaging nanosized extracellular vesicles derived from mesenchymal stem cells as novel therapeutic tools and to control undesired immune responses in translational nanomedicine. During his trajectory, he has also paved the way for elucidation of the basis governing idiopathic dilated cardiomyopathy, the most frequent etiology of non ischemic heart failure, and to developing further treatments to counteract irreversible myocardial damage, as well as clinically relevant blood markers with diagnostic and prognostic value. In 2016 he was contracted as a Researcher Associate by CMR[B] to specifically collaborate in several long-term projects focused in novel approaches of cardiac tissue engineering.
Research Interest
Molecular Biology, Cell Biology, Methods, Biomedical Engineering, PCR, Stem Cell Biology, Tissue Engineering, Biomaterials
Publications
-
Iborra-Egea O, Galvez-Montón C, Roura S, Perea-Gil I, Prat-Vidal C, Soler-Botija C, Bayes-Genis A. (2017) Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach. Systems Biology and Applications eCollection 2017: 3-12. Epub 2017, Apr 18.
-
EcheverrÃa P, Gómez-Mora E, Roura S, Bonjoch A, Puig J, Pérez-Alvarez N, Bayes-Genis A, Clotet B, Blanco J, Negredo E. (2017) Variable Endothelial Cell Function Restoration after Initiation of two Antiretroviral Regimens in HIV-Infected Individuals. J Antimicrob Chemother Mar 22 [Epub ahead of print].
-
Bobi J, Solanes N, Fernández-Jiménez R, Galán-Arriola C, Dantas AP, Fernández-Friera L, Gálvez-Montón C, Rigol-Monzó E, Agüero J, RamÃrez J, Roqué M, Bayes-Genis A, Sánchez-González J, GarcÃa-Ãlvarez A, Sabaté M, Roura S, Ibáñez B, Rigol M. (2017) Intracoronary Administration of Allogeneic Adipose Tissue–Derived Mesenchymal Stem Cells Improves Myocardial Perfusion But Not Left Ventricle Function, in a Translational Model of Acute Myocardial Infarction. J. Am. Heart Assoc. May 3 [Epub ahead of print].
-
Roura S, Gálvez-Montón C, de Gonzalo-Calvo D, Valero AG, Gastelurrutia P, Revuelta-López E, Prat-Vidal C, Soler-Botija C, Llucià -Valldeperas A, Perea-Gil I, Iborra-Egea O, Borràs FE, Lupón J, Llorente-Cortés V, Bayes-Genis A (2017) Extracellular vesicles do not contribute to higher circulating levels of soluble LRP1 in idiopathic dilated cardiomyopathy. J Cell Mol Med. May 29 [Epub ahead of print].
