Jesús M. Paramio

Biography

 Jesús M. Paramio is currently the Director of the Molecular Oncology Unit at CIEMAT (Center for Energy, Environment and Technology Research) in Madrid (Spain). He obtained his Ph.D. in Biology at the University Autonoma of Madrid and was a postdoctoral fellow at the Medical Sciences Institute in the University of Dundee and at the National Institute of Dental and Craniofacial Research of the NIH (Bethesda USA). He has more than 70 articles published in international scientific journals and is co-author of four patents for the genomic prognostic signatures of human cancers. Dr. Paramio laboratory is focused on the generation of different mouse models through different genetic manipulation approaches affecting different tumor suppressor genes (Rb family, p53, Pten) or oncogenes (Akt) in certain epithelial tissues. These models were specifically designed to mimic different types of human cancer. More recently, his lab has focused on the identification of genomic alterations in human and mouse samples in order to validate the mouse models as preclinical tools for the study of experimental new therapeutics in cancer and the characterization of possible cancer stem cells in human and rodent specimens.

Research Interest

 General Science