Eyras JimÉnez, Eduardo
Research Professor
Life & Medical Sciences
Institucio Catalana de Recerca i Estudis Avancats
Spain
Biography
Eduardo Eyras is ICREA Research Professor since January 2005. After graduating in Physics (U. of Granada, 1995) he did a PhD (U. of Groningen, The Netherlands, 1999) and postdoc (U. of Cambridge, UK) in Theoretical Physics (1999-2001). During this period, he published 15 articles, which accumulate more than 900 citations. In 2001, Eyras joined the Wellcome Trust Sanger Institute, Cambridge, UK (2001-2004), where he developed one of the first methods to predict splicing variants from RNA expression data and participated in the analyses of the human, mouse and rat genomes. During 2004 he contributed to the analyses of alternative splicing in the chicken and cow genome genomes. Since 2007, Eyras has been organizer of the RNA workshop of the ISMB conference. In 2008, he was awarded a Young Investigator Grant of the EURASNET network and in 2013 he was a visiting professor at the U. of Toronto.
Research Interest
Their group works on the development of computational tools to study mechanisms of RNA processing and its role in disease. In particular, they have a strong focus on the study of RNA splicing regulation and the role of RNA splicing in rare diseases and cancer.
Publications
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Zhang R, Calixto CP, Tzioutziou NA, James AB, Simpson CG, Guo W, Marquez Y, Kalyna M, Patro R, Eyras E, Barta A, Nimmo HG, Brown JW (2015). AtRTD - a comprehensive reference transcript dataset resource for accurate quantification of transcript-specific expression in Arabidopsis thaliana. New Phytol 208(1):96-101
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González-Vallinas J, Pagès A, Singh B, Eyras E (2015). A semi-supervised approach uncovers thousands of intragenic enhancers differentially activated in human cells. BMC Genomics 16:523
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Kremsky I, Bellora N, Eyras E (2015). A Quantitative Profiling Tool for Diverse Genomic Data Types Reveals Potential Associations between Chromatin and Pre-mRNA Processing. PLoS One 10(7):e0132448.
