MarquÈs Bonet, TomÀs
Research Professor
Life & Medical Sciences
Institucio Catalana de Recerca i Estudis Avancats
Spain
Biography
Dr. Marquès-Bonet is the Principal Investigator of the group "Comparative Genomics" at the Institute of Evolutionary Biology (IBE; UPF/CSIC) and at the CRG-CNAG. He started his own lab in 2010 with an ERC Starting Grant and was selected as ICREA in 2011. In 2013 he was selected for the EMBO young Investigator award. He has been part of many genome consortia, leading the section of duplications and structural variation in most of them. Starting in 2016, he is the vice-director of the Institute of Evolutionary Biology. His group wants to characterize human specific genomics features, including the evolution of epigenetics in humans or the impact of CNVs in phenotypic traits. With a total of more than 80 peer-reviewed publications, he has published as a senior authorship in Science (2016), Nature (2013), Genome Research (2015), Plos Genetics (2013,2015) among others.
Research Interest
What makes us human? This is a fundamental question in many disciplines. Our team analyzes a wide range of genome variants to determine processes, variants and molecular features that are intrinsic to our species. To do so, we study full genome, epigenomes and transcriptomic sequences of humans and great apes for a better understanding of human specific features.
Publications
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Byrappa Venkatesh, Alison P. Lee, Vydianathan Ravi, Michelle M. Lian, Ashish K. Maurya, Jeremy B. Swann, Yuko Ohta, Martin F. Flajnik, Yoichi Sutoh, Masanori Kasahara, Shawn Hoon, Vamshidhar Gangu, Scott W. Roy, Manuel Irimia, Vladimir Korzh, Igor Kondrychyn, Boonâ€Hui Tay, Sumanty Tohari, Zhi Wei Lim1, Kiat Whye Kong, Shufen Ho, Belen Lorenteâ€Galdos, Javier Quilez, Tomas Marquesâ€Bonet, Brian J. Raney, Philip W. Ingham, Alice Tay, LaDeana W. Hillier, Patrick Minx, Thomas Boehm, Richard K. Wilson, Sydney Brenner & Wesley C. Warren. “The elephant shark genome provides unique insights into gnathostome evolutionâ€. Nature. 2014 Jan 9;505(7482):174â€9
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Michael J. Montague, Gang Li, Barbara Gandolfi, Razib Khan, Bronwen L. Aken, Steven M. J. Searle, Patrick Minx, LaDeana Hillier, Daniel C. Koboldt, Brian W. Davis, Carlos A. Driscoll, Christina Barr, Kevin Blackistone, Javier Quilez, Belen Lorenteâ€Galdos, Tomas Marquesâ€Bonet, Can Alkan, Gregg W.C. Thomas, Matthew W. Hahn, Marilyn Menottiâ€Raymond, Stephen J. O’Brien, Richard K.  Wilson, Leslie A. Lyons, William J. Murphy, Wesley C. Warren. “Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication.†PNAS 2014 Â
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Oscar Ramirez, Iñigo Olalde, Jonas Berglund, Belen Lorenteâ€Galdos, Matthew T. Webster, Robert K. Wayne, Carles Laluezaâ€Fox, Carles Vilà , Tomas Marquesâ€Bonet. “Analysis of structural diversity in wolf†like canids reveals postâ€domestication variants.†BMC genomics 2014 Jun 12;15:465.
