Vernos, Isabelle
Research Professor
Life & Medical Sciences
Institucio Catalana de Recerca i Estudis Avancats
Spain
Biography
1989-1992 PhD UAM, Madrid, Spain 1989-1992 Postdoc, Wellcome/CRC Institute, Cambridge, UK 1992-1996 Postdoc, EMBL, Heidelberg, Germany 1996-2001 Staff Scientist, EMBL, Germany 2001-2005 Team Leader, EMBL, Germany Since 2005 ICREA Research Professor, CRG, Barcelona, Spain Since 2005, EMBO member Since 2011, member of the ERC Scientific Council 2015 Narcis Monturiol medal
Research Interest
Life depends on the ability of cells to divide while maintaining their genomic integrity. Cell division is therefore a critical process and yet involves the full reversible reorganization of the intra-cellular components. We are currently trying to understand the mechanism and regulatory signalling pathways involved in the transient formation of the mitotic spindle, the microtubule based molecular machine that segregates the chromosomes during cell division.
Publications
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Young J., Stauber T., del Nery E., Vernos I., Pepperkok R. and T, Nilsson.(2005)Regulation of microtubule-dependent recycling at the TGN by rab6A and rab6A'.Mol Biol Cell. 16(1):162-77
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Gartner M., Sunder-Plassmann N., Seiler J., Utz M., Vernos I., Surrey T,Giannis T. (2005)Development and Biological Evaluation of Potent and Specific Monastrol Analogues as Inhibitors of Mitotic Kinesin Eg5. ChemBioChem. 6(7):1173-7.
