Sergi Puig TodolÃ
professor
food science
Instituto de Agroquímica y Tecnología de Alimentos
Spain
Biography
Iron is an essential micronutrient for all eukaryotes. However, iron deficiency anemia is the most extended nutritional disorder worldwide. Thus, our main objective consists on deciphering the molecular mechanisms that eukaryotic cells utilize to regulate the response to iron deficiency. For this purpose, we use the yeast Saccharomyces cerevisiae as a model organism and biotechnological tool, paying special attention to transcriptional, post-transcriptional and metabolic regulation strategies. We use a multidisciplinary approach that includes Molecular Biology, Biochemistry, Microbiology, Genetics, Cellular Biology and "Omic" techniques.
Research Interest
FOOD BIOTECHNOLOGY
Publications
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Regulation of ribonucleotide reductase in response to iron deficiency.
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Negative feedback regulation of the yeast Cth1 and Cth2 mRNA binding proteins is required for adaptation to iron deficiency and iron supplementation.
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Yeast Dun1 kinase regulates ribonucleotide reductase inhibitor Sml1 in response to iron deficiency
