Enrique Lara Pezzi
Group Leader
Molecular Regulation of Heart Failure
National Cardiovascular Research Center Carlos
Spain
Biography
Enrique Lara-Pezzi holds a degree in Chemical Sciences from the Universidad Autónoma de Madrid (1995) and a doctorate in Biochemistry and Molecular Biology from the same university (2000). His doctoral thesis, carried out in the laboratory of Manuel López-Cabrera at the Hospital Universitario de la Princesa, in Madrid, focused on the study of the HBx protein from the hepatitis B virus and his contribution to the immune response and to the hepatocellular development. After a first postdoctoral stay in the laboratory of Dr. López-Cabrera, during which the study of the HBx protein continued. In 2003 he joined the laboratory of Prof. Nadia Rosenthal (European Molecular Biology Laboratory, Monterotondo, Italy), where she studied the contribution of the calcineurin isoform CnAß1 to regeneration of skeletal muscle until 2006. With funding from the Marie Curie program, she moved to the laboratory of Prof. Nadia Rosenthal at the Heart Science Center (Imperial College London) to investigate the molecular mechanisms that mediate heart failure and regeneration of the cardiac tissue (2006-2009). Enrique joined the CNIC in 2009.
Research Interest
Cardiology
Publications
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López-Olañeta MM, Villalba M, Gómez-Salinero JM, Jiménez-Borreguero LJ, Breckenridge R, Ortiz-Sánchez P, GarcÃa-PavÃa P, Ibáñez B, Lara-Pezzi E. Induction of the calcineurin variant CnAβ1 after myocardial infarction reduces post-infarction ventricular remodelling by promoting infarct vascularization. Cardiovascular research. 2014 Mar 25;102(3):396-406.
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Gatto A, Torroja-Fungairiño C, Mazzarotto F, Cook SA, Barton PJ, Sánchez-Cabo F, Lara-Pezzi E. FineSplice, enhanced splice junction detection and quantification: a novel pipeline based on the assessment of diverse RNA-Seq alignment solutions. Nucleic acids research. 2014 Feb 25;42(8):e71-.
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Lara-Pezzi E, Menasché P, Trouvin JH, Badimón L, Ioannidis JP, Wu JC, Hill JA, Koch WJ, De Felice AF, de Waele P, Steenwinckel V. Guidelines for translational research in heart failure. Journal of cardiovascular translational research. 2015 Feb 1;8(1):3-22.