Dr. Ana Carmena
European neuroscience institute
Network of European Neuroscience Institutes (ENI-NET)
Spain
Biography
Dr. Ana Carmena Laboratory PDZ proteins and Signaling Networks during the specification of neuronal identities – The Instituto de Neurociencias de Alicante
Research Interest
PDZ (PSD-95, Dlg, ZO-1) domain-containing proteins are excellent candidates as hubs of cross-talk between signaling cascades during Development. In addition, malfunction of many PDZ proteins has been linked to diverse neuropathologies and types of cancer. The aim of our research is to analyze the function of PDZ proteins, including the cytoplasmic protein Canoe/AF-6, as signal integrators within signaling networks during the acquisition of unique cell fates throughout nervous system development.