Antonia Gutiérrez Pérez
Professor
Department of Cell Biology, Genetics and Physiology
Universidad de Malaga
Spain
Biography
Antonia Gutiérrez Pérez holds a PhD in Biological Sciences from the University of Málaga (1991). After a postdoctoral scientific specialization of three years in the United States, she returned to the UMA in 1994 with a Contract of Reincorporation of the Ministry of Education and Science and later as Full Professor of Cell Biology (1995-2010). Since 2011 she is Professor of Cell Biology at the University of Málaga.Since 2007 she is Principal Investigator of the Center for Biomedical Research in Network on Neurodegenerative Diseases (CIBERNED), an organization belonging to the Carlos III Health Institute and designated as a Center of Excellence within the CoEN International Network at the proposal of the European Union. Her group is part of CIBERNED Program 1 dedicated to Alzheimer's disease and other related dementias (www.ciberned.es).
Research Interest
Preclinical effectiveness of new therapeutic treatments.
Publications
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Pintado C, Gavilán MP, Gavilán E, GarcÃa-Cuervo L, Gutiérrez A, Vitorica J, Castaño A, RÃos RM, Ruano D. Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus. Journal of neuroinflammation. 2012 May 4;9(1):87.
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Sanchez-Varo R, Trujillo-Estrada L, Sanchez-Mejias E, Torres M, Baglietto-Vargas D, Moreno-Gonzalez I, De Castro V, Jimenez S, Ruano D, Vizuete M, Davila JC. Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus. Acta neuropathologica. 2012 Jan 1;123(1):53-70.
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Torres M, Jimenez S, Sanchez-Varo R, Navarro V, Trujillo-Estrada L, Sanchez-Mejias E, Carmona I, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus. Molecular neurodegeneration. 2012 Nov 22;7(1):59.
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Trujillo-Estrada L, Jimenez S, De Castro V, Torres M, Baglietto-Vargas D, Moreno-Gonzalez I, Navarro V, Sanchez-Varo R, Sanchez-Mejias E, Davila JC, Vizuete M. In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology. Acta neuropathologica communications. 2013 Nov 12;1(1):73.
