José Manuel Fernández-fÃgares
Professor
Department of Cell Biology, Genetics and Physiology
Universidad de Malaga
Spain
Biography
José-Manuel Fernández-Fígares Pérez (JM Pérez-Fígares) holds a degree from the University of Granada (1975) and a PhD in Biological Sciences from the University of Málaga (1979). Adjunct Professor of Cytology and Histology in 1978 and Professor of Cell Biology since 2002, at the University of Málaga. He has been Secretary of the Faculty of Sciences (1986-88), director of the Department of Cell Biology, Genetics and Physiology since 1988-94 and Coordinator of Tests of Access to the University since 1999. His scientific career has been completed with stays at the Faculty of Medicine of the Universidad Austral de Chile, in Valdivia (Chile).
Research Interest
Congenital hydrocephalus and the search for therapies for its treatment.
Publications
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Bátiz F, Roales-Buján R, RodrÃguez-Perez LM, Matas IM, Páez P, Roque M, Jiménez AJ, Ramos C, Pérez-FÃgares JM. A simple PCR-based genotyping method for M105I mutation of alpha-SNAP enhances the study of early pathological changes in hyh phenotype Molecular and Cellular Probes 23: 281-290 (2009)
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Jiménez AJ, GarcÃa-Verdugo JM, González CA, Bátiz LF, RodrÃguez-Pérez LM, Páez P, Soriano-Navarro M, Roales-Buján R, Rivera P, RodrÃguez S, RodrÃguez EM, Pérez-FÃgares JM. Disruption of the neurogenic niche in the subventricular zone of postnatal hydrocephalic hyh mice. J Neuropathol Exp Neurol. 68: 1006-20 (2009)
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Batz LF, Jiménez AJ, Guerra M, RodrÃguez-Pérez LM, Toledo CD, Vio K, Páez P, Pérez-FÃgares JM and RodrÃguez EM. New ependymal cells are born postnatally in two discrete regions of the mouse brain and support ventricular enlargement in hydrocephalus. Acta Neuropathologica 121: 721-735 (2011)
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RodrÃguez EM, Guerra M, VÃo K, González C, Ortloff A, Bátiz LF, RodrÃguez S, Jara M, Muñoz R, Ortega E, Jaque J, Guerra F, Sival DA, den Dunnen WFA, Jiménez A, DomÃnguez-Pinos MD , Pérez-FÃgares JM, McAllister JP, Johanson C. A cell junction pathology of neural stem cells leads to abnormal neurogenesis and hydrocephalus. Biological Reserch 45: 231-241 (2012)
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Roales-Buján R, Páez P, Guerra M, RodrÃguez S, Vio K, Ho-Plagaro A, GarcÃa-Bonilla M, RodrÃguez-Pérez LM, DomÃnguez-Pinos MD, RodrÃguez EM, Pérez-FÃgares JM, Jiménez AJ. Astrocytes acquire morphological and functional characteristics of ependymal cells following disruption of ependyma in hydrocephalus. Acta Neuropathologica 124: 531-546 (2012)
