José MarÃa Pérez Pomares
Professor
Department of Animal Biology
Universidad de Malaga
Spain
Biography
PhD in Biological Sciences at the University of Málaga. Following his doctoral thesis, he began research on the embryonic development of the vertebrate heart and its relation to diseases of the cardiovascular system. These investigations continued in the USA thanks to a postdoctoral fellowship funded by the National Institutes of Health (NIH) and the Medical University of South Carolina (2000-2002) and then again in Spain following his reinstatement as Assistant Professor at The UMA. He is currently a Full Professor in the Department of Animal and Visiting Scientific Biology of the National Center for Cardiovascular Research (CNIC-ISCIII) in Madrid, where he works as a teacher (graduate and postgraduate) and researcher. I have participated in 15 research projects (in 7 of them as principal investigator) financed by national institutions (National R & D & I, ISCIII, Junta de Andalucía) and international institutions (EU Framework Programs for Research, Science Program Of NATO Life) and is the author of over 45 scientific articles published in international journals. He has lectured at prestigious academic and research centers (Harvard University, Boston, USA, Mount Sinai Hospital & School of Medicine, New York, USA, University of Amsterdam, The Netherlands, Leiden University, The Netherlands, University of Tromsø, Norway; University of Padua, Italy, Tokyo Women's University, Tokyo, Japan, among others).
Research Interest
Cardiovascular Development and Angiogenesis
Publications
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Azambuja AP, Portillo-Sánchez V, Rodrigues MV, Omae SV, Schechtman D, Strauss BE, Costanzi-Strauss E, Krieger JE, Perez-Pomares JM, Xavier-Neto J. Retinoic acid and VEGF delay smooth muscle relative to endothelial differentiation to coordinate inner and outer coronary vessel wall morphogenesis. Circulation research. 2010 Jul 23;107(2):204-16.
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Luna-Zurita L, Prados B, Grego-Bessa J, Luxán G, del Monte G, BengurÃa A, Adams RH, Pérez-Pomares JM, de la Pompa JL. Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. The Journal of clinical investigation. 2010 Oct 1;120(10):3493.
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Guadix JA, Ruiz-Villalba A, Lettice L, Velecela V, Muñoz-Chápuli R, Hastie ND, Pérez-Pomares JM, MartÃnez-Estrada OM. Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2. Development. 2011 Mar 15;138(6):1093-7.
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Pérez-Pomares JM, de la Pompa JL. Signaling during epicardium and coronary vessel development. Circulation research. 2011 Dec 9;109(12):1429-42.
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Ruiz-Villalba A, Ziogas A, Ehrbar M, Pérez-Pomares JM. Characterization of epicardial-derived cardiac interstitial cells: differentiation and mobilization of heart fibroblast progenitors. PloS one. 2013 Jan 18;8(1):e53694.
