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Maria Dolores López Ávalos

Professor
Department of Cell Biology, Genetics and Physiology
Universidad de Malaga
Spain

Biography

She received a Bachelor's degree in Biological Sciences from the University of Málaga in 1990 and a PhD from the same university in 1995, with a work on the study of the glycoprotein secretion of the subcommissural organ, a brain gland whose function is not well defined. Since 1995 she has developed her postdoctoral training in the United States. First at UMASS Medical Center (Worcester, MA), working on glycosylation in yeast (1995-1997). Subsequently at Joslin Diabetes Center (Boston, MA), dedicated to obtaining and improving beta cells for transplantation in diabetes (1998-2001). In 2002 she joined the Physiology area of ​​the Department of Cell Biology, Genetics and Physiology at the University of Málaga as an Assistant Professor. In 2004 she became a Ph.D. Professor and in 2011 she was Professor. During this time, she teaches in various subjects of Animal Physiology of degrees in the field of Biological Sciences, as well as in the Master of Advanced Biotechnology of the UMA.

Research Interest

Neuroscience, in particular in neurogenesis in adult individuals, in different aspects of the biology of ependymal cells that cover the cerebral ventricles, and in a neuroinflammation and demyelination model provoked by neuraminidase

Publications

  • Hoyo-Becerra C, López-Avalos MD, Cifuentes M, Visser R, Fernández-Llebrez P, Grondona JM. The subcommissural organ and the development of the posterior commissure in chick embryos . Cell Tissue Res. 339 (2): 383-395 (2010).

  • Lopez-Avalos MD , Duvivier-Kali VF , Xu G , Bonner-Weir S , Sharma A , Weir GC . Evidence for a role of the ubiquitin-proteasome pathway in pancreatic islets. Diabetes. 55 (5): 1223-1231 (2006).

  • Xu G , Kaneto H , Lopez-Avalos MD , Weir GC , Bonner-Weir S . GLP-1 / exendin-4 facilitates beta-cell neogenesis in rat and human pancreatic ducts. Diabetes Res Clin Pract. 73 (1): 107-110 (2006).

  • Lopez-Avalos MD, Tatarkiewicz K, Sharma A, Bonner-Weir S, Weir GC. Enhanced maturation of neonatal porcine pancreatic cell clusters with growth factors fails to improve transplantation outcome. Transplantation 71 (8): 1154-1162 (2001).

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