Katritch’s research is focused on deciphering the molecular mechanisms of G protein-coupled receptors (GPCRs) and using this knowledge to design ligands with specific functional properties. These studies employ molecular modeling and structural bioinformatics analysis of crystallographic, biophysical, pharmacological and other experimental data to probe interactions and conformational dynamics of GPCRs. Katritch’s work has resulted in five patents and more than 70 publications, including prospective ligand-discovery studies, as well as high impact reviews on GPCR structure and function. Before joining USC, he held faculty positions at The Scripps Research Institute and the University of California, San Diego School of Pharmacy and San Diego Supercomputer Center.
Dr. Katritch has also served as director of computational biology for Plexus Vaccine and SiGA Technologies. He completed his Ph.D. in Biophysics and Molecular biology at Moscow Institute of Physics and Technology, and postdoctoral training at Lausanne University and Rutgers University.