Ann-sofie Cans
Associate professor
Chemistry and Chemical Engineering
Chalmers University of Technology
Sweden
Biography
At Chalmers I am now pioneering a research program with a focus on nanosensor engineering and artificial cell structures to study the chemistry and biophysics of cells, and neuronal communication. Currently running projects involve development and application of artificial cell models to study 1) quantitative amperometric measurements on the effects of lipids composition in membrane dynamics and sorting inhigh curvature regions of nanotube biomembranes, 2) DNA-zipper-catalyzed artificial exocytosis, and 3) development of millisecond time resolved ultra-small biosensors constructed from enzyme nanoparticle bioconjugates for selective probing of molecules in vivo in the brain.
Research Interest
nanosensor engineering and artificial cell structures
Publications
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Karlsson M, Sott K, Davidson M, Cans AS, Linderholm P, Chiu D, Orwar O. Formation of geometrically complex lipid nanotube-vesicle networks of higher-order topologies. Proceedings of the National Academy of Sciences. 2002 Sep 3;99(18):11573-8.
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Cans AS, Wittenberg N, Karlsson R, Sombers L, Karlsson M, Orwar O, Ewing A. Artificial cells: unique insights into exocytosis using liposomes and lipid nanotubes. Proceedings of the National Academy of Sciences. 2003 Jan 21;100(2):400-4.
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Karlsson A, Karlsson R, Karlsson M, Cans AS, Strömberg A, Ryttsén F, Orwar O. Molecular engineering: networks of nanotubes and containers. Nature. 2001 Jan 11;409(6817):150.
