Leif Bertilsson
Associate Prof.
Laboratory Medicine
Karolinska Institutet
Sweden
Biography
Prof Leif Bertilsson is currently working as Professor Karolinska Institutet, Department of Laboratory Medicine.
Research Interest
Clinical Pharmacology
Publications
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Kanebratt KP, Diczfalusy U, Bäckström T, Sparve E, Bredberg E, Böttiger Y, Andersson TB, Bertilsson L. Cytochrome P450 induction by rifampicin in healthy subjects: determination using the karolinska cocktail and the endogenous CYP3A4 marker 4βâ€hydroxycholesterol. Clinical Pharmacology & Therapeutics. 2008 Nov 1;84(5):589-94.
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Bertilsson L. Metabolism of antidepressant and neuroleptic drugs by cytochrome p450s: clinical and interethnic aspects. Clinical pharmacology & therapeutics. 2007 Nov 1;82(5):606-9.
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Mirghani RA, Sayi J, Aklillu E, Allqvist A, Jande M, Wennerholm A, Eriksen J, Herben VM, Jones BC, Gustafsson LL, Bertilsson L. CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population. Pharmacogenetics and genomics. 2006 Sep 1;16(9):637-45.
