Kristian Pietras

Biography

We aim to molecularly map the support functions performed by the various cell types comprising the tumor microenvironment. We believe that decisive treatment benefit can only be achieved by targeting distinct cell types and pathways that collectively sustain tumor growth. Specifically, molecular interactions between cancer-associated fibroblasts, pericytes and endothelial cells are explored with a special focus on novel anti-cancer strategies. Importantly, the cellular networks within tumors cannot be studied in isolation. Thus, our work ranges over many different topics, with methodology, technology and purpose as the common denominators. We aim to molecularly map the support functions performed by the various cell types comprising the tumor microenvironment. We believe that decisive treatment benefit can only be achieved by targeting distinct cell types and pathways that collectively sustain tumor growth. Specifically, molecular interactions between cancer-associated fibroblasts, pericytes and endothelial cells are explored with a special focus on novel anti-cancer strategies. Importantly, the cellular networks within tumors cannot be studied in isolation. Thus, our work ranges over many different topics, with methodology, technology and purpose as the common denominators.

Research Interest

Cancer and Oncology Tumor microenvironment , Targeted therapy, Mouse models of cancer