Urban Ungerstedt

Biography

Ungerstedt has pioneered the microdialysis technique, which he developed together with his group at Karolinska Institutet already at the beginning of the 1970s. Since then more than 15 000 papers were published describing the use of microdialysis in pharmacology, physiology, clinical monitoring and other related biomedical fields. These studies refer basically to the same principle, probe design and experimental set-up as originally described by Ungerstedt and Pycock. Besides development of microdialysis, Dr. Ungerstedt made several major contributions to current understanding of functional neuroanatomy of the monoaminergic systems, with particular focus on the dopaminergic system in the basal ganglia. His seminal discovery on 6-hydroxydopamine selective lesions of the nigro-striatal dopamine pathway and measuring turning behaviour induced by dopamimetic drugs is still used as the most important rodent model of Parkinson´s disease

Research Interest

 Clinical research