Alexander

Biography

Ph.D., Associate Professor, Integrative Physiology and Pathobiology, Tufts University Dr. Poltorak is an associate professor at Tufts University School of Medicine where he focuses on innate immunity and on the inflammatory. His lab recently discovered that STING, a mediator of responses to cytosolic DNA, plays a role not just in innate immunity, the body’s first line of defense, but also in T cells, part of the adaptive immune response. These observations imply that STING-targeted therapeutics needs to specifically be examined for possible long-term effects on T cell immunity, such as potential T cell deficiencies. Conversely, these findings potentially suggest that targeting STING in T cells could be beneficial for the elimination of pathological T cells in the case of T cell lymphomas, or autoimmune disease,

Research Interest

Dentistry