Joerg Betschinger
Biology
Friedrich Miescher Institute for Biomedical Research
Switzerland
Biography
2013 Junior Group Leader; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland 2007-2013 Research Associate; Wellcome Trust/MRC Stem Cell Centre, University of Cambridge, UK 2004-2006 Postdoctoral Fellow; Institute of Molecular Biotechnology, Vienna, Austria
Research Interest
Our research aims at deciphering mechanisms and logics driving cell state transitions using pluripotent stem cells as a paradigm. In particular, by combining genetic and biochemical approaches, we target the identification of modules that regulate cell state changeover, to specify the underlying network dynamics, and to deduce routines conferring network plasticity.
Publications
-
Betschinger J, Mechtler K, Knoblich JA (2006) Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells. Cell 124(6): 1241-53
-
Betschinger J, Nichols J, Dietmann S, Corrin PS, Paddison PJ, Smith A (2013) Exit from Pluripotency is Gated by Intracellular Redistribution of the bHLH Transcription Factor Tfe3. Cell 153(2): 335-47
