Marie-agnes Doucey

Biography

I am a project leader in the interdisciplinary team led by Ludwig Lausanne director George Coukos, in charge of the tumor microenvironment and systems immunopharmacology line of work at the lab complex led by the director. I was educated as both a biologist and a biotechnological engineer in France and received a Ph.D. in Biochemistry at the Friedrich-Miescher Institute (Novartis, Basel, Switzerland). In 2004, I began working as a project leader at the Lausanne University Hospital (Centre Hospitalier Universitaire Vaudois, CHUV), where I hired my first research group. I have since obtained continuous funding for my own research projects. My studies focused primarily on the activation of human memory T cells before I began leading an interdisciplinary program combining experimental oncology, Boolean system modeling and nano-biosensors to predict the behavior of immune-suppressive angiogenic monocytes in human breast cancer. In January 2013, Dr. Coukos invited me to lead the tumor microenvironement and systems immunopharmacology program in his newly established laboratory here, and my research group was integrated into that program. Our primary goal is to develop interventions targeting the tumor microenvironment to rescue and reprogram dysfunctional cancer-specific tumor infiltrating lymphocytes for their use in the personalized treatment of cancer.

Research Interest

Immunopharmacology,tumor biology, cancer therapeutics